NCBI provides a wealth of tools, resources, and learning materials to promote "...finding new approaches to deal with the volume and complexity of data and to provide researchers with better access to analysis and computing tools to advance understanding of our genetic legacy and its role in health and disease."
Key Resources in addition to PubMed include:
Gene - data, information, and literature for known and predicted genes
Protein - sequences of protein, mRNA
Structure - 3D structures database of macromolecules, with multiple tools
Nucleotide - a collection of nucleotide sequences from several sources within and outside of NCBI databases